Salt sensitive: Participants with SBP being at least 5 mmHg higher after HS intake compared to the values after the LS intake; Salt resistant: Participants whose SBP differed by <5 mmHg between HS and LS intakes; Independent variables: Urinary Na + , Urinary K + and Na + :K + excretion ratio; Dependent variable: SBP; Categorical variable: Participants were categorized into groups on the basis of increments of 1 g/day in urinary Na + and K + excretion to evaluate the linear trends
Analytical research
General linear habits was useful for linear regression studies (Pearson’s Roentgen correlation) to assess the newest connection out of urinary Na + and you can K + removal having SBP. For Figs. dos and you can 3, two-means ANOVA which have Tukey’s blog post hoc was did examine SBP among communities laid out on the basis of urinary Na + and you can K + removal. To assess the effectiveness of expanding urinary Na + and K + removal according to SBP, Cohn’s Effect Proportions are calculated. From inside the Figs. cuatro and you may 5 generalized Pearson’s Roentgen relationship is actually performed to evaluate new organization of your own urinary Na + :K + excretion ratio with SBP. During the Fig. 6 analysis was indeed reviewed by the a good around three-means ANOVA and also the pairwise comparisons were made using Tukey’s article hoc test. In Fig. eight relative frequency shipments are reviewed playing with a great Gaussian match analysis. 05 (GraphPad prism application, adaptation 8). Research is shown due to the fact indicate ± SD.
Baseline systolic blood pressure (SBP) at screening on regular diet (a) according to changes potassium excretion for salt sensitive (n = 186) and salt resistant (n = 222) group, slope for salt sensitive and salt resistant group is indicated for the potassium excretion range <1–1
Baseline systolic blood pressure (SBP) at screening on regular diet (a) according to changes sodium excretion of <5 g/day, in salt sensitive (n = 154) and salt resistant (n = 180) group, slope of the for salt sensitive group is indicated for the sodium excretion ranges of <2–2.99 g/day, 3–3.99 g/day and 4–4.99 g/day (b) Correlation of baseline SBP (dependent variable) across the entire range of urinary sodium excretion (independent variable), (Pearson's R 2 for salt sensitive = 0.02 and for salt resistant = 0.02), in salt sensitive (n = 186) and salt resistant (n = 222) individuals.
99 g/day, opinions shown given that mean ± SD. b Correlation regarding standard SBP (centered adjustable) across the entire variety urinary potassium excretion (independent variable), (Pearson’s R dos for salt sensitive = 0.001 and you may sodium unwilling = 0.008), in salt sensitive and painful (letter = 186) and you will salt unwilling (letter = 222) some body.
Standard SBP prior to urinary sodium in order to potassium excretion ratio (Na + /K + ) (a) correlation out of baseline SBP (established changeable) along side whole listing of urinary Na + /K + excretion (separate adjustable), (Pearson’s Roentgen 2 for salt sensitive = 0.0004 and you may sodium resistant = 0.0016) (b) baseline SBP based on changes in salt excretion and you can potassium removal assortment in the sodium painful and sensitive (letter = 186) and you will salt resistant (n = 222) somebody on screening on the regular diet plan, viewpoints revealed given that suggest ± SD. Study had been examined from the around three-ways ANOVA with pairwise review followed by Tukey’s post hoc decide to try.
Correlation regarding SBP values across the entire listing of urinary salt to help you potassium excretion (Na + /K + ) proportion in sodium sensitive (n = 71) and you will salt resistant (n = 119) people with fat loss intervention of one’s Weightloss Approaches to Prevent Blood pressure levels (DASH) (a) large salt (HS), (Pearson’s R 2 to possess salt sensitive and painful = 0.04 and you will salt unwilling = 0.04) (b) reasonable sodium (LS) diet plan, (Pearson’s R dos getting 
sodium painful and sensitive = 0.02 and you may salt unwilling = 0.00002).